Breast cancer

Immunotherapy for breast cancer

Overview

Immunotherapy helps your body's immune system find and attack cancer cells. Pembrolizumab is a type of immunotherapy drug that may be used to treat some types of triple-negative breast cancer.

Side effects can include tiredness, rash, diarrhoea, breathlessness, joint pain and inflammation in different parts of the body. Tell your treatment team about any side effects as soon as possible, as most can be treated more easily when found early.

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About immunotherapy

Immunotherapy is a treatment that uses the body’s own immune system to fight cancer. A drug called pembrolizumab may be used for people with certain types of triple negative breast cancer. Pembrolizumab is used together with a chemotherapy drug. Pembrolizumab is given through a vein (intravenously), and treatments usually take about 30 minutes.

Side effects of immunotherapy

These may be caused by the immunotherapy, the chemotherapy or both. Common side effects include a rash, fatigue, diarrhoea (which can be severe), breathlessness, joint pains, diabetes, nerve problems, muscle weakness and dry eyes. It can cause inflammation in other organs, including the thyroid, pituitary gland, liver, kidneys and pancreas. It can also affect the adrenal gland, which can lead to low levels of certain hormones (e.g. cortisol). If you notice these or any other side effects, it’s important to let your treatment team know – some side effects can be life-threatening if left untreated.

Most side effects, however, can be managed if they are reported early. Sometimes, immunotherapy may need to be stopped or interrupted. Side effects from immunotherapy can occur for up to 12 months after the last dose was given. Pregnancy should be avoided during this time.

More information

Learn more about Immunotherapy, or for more about managing the effects of immunotherapy, see Managing side effects of breast cancer treatment.

Relevant support

Breast Cancer Network Australia

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McGrath Foundation

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